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Collectively these processes may ultimately lead to the death of neurons

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10.2174/1573399814666180924113442 146 NakhodV.KrivenkoA.ButkovaT.MalsagovaK.KayshevaA
Thus, disorders of hereditary iron overload can cause iron deposition in tissues that might result in hypogonadism and impaired spermatogenesis, whereas severe iron deficiency can propagate anaemias that decrease gonadotropin release and sperm counts

Rodier et al., 2009