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In subsequent sections, we will delve into the mechanisms through which NNMT activity contributes to diminished NAD + levels and augmented Hcy levels, respectively, and their implications in the context of MetS

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Other markers of glial reactivity are cytokines, complement pathway mediators, purinergic receptors, CX3C motif chemokine receptor 1 (CX3CR1), colony stimulating factor 1 receptor (CSF1R), and triggering receptor expressed on myeloid cells 2 (TREM2) (imoniov et al., 2021)