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By silencing NNMT, it enables a natural uptick in NAD levels, leading to enhanced mitochondrial function, lean mass preservation, and fat metabolism without overstimulation

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However, for visceral fat specifically, tesamorelin shows the most dramatic reduction in the deep abdominal compartment

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Early haematological response begins with reticulocytosis (increased production of immature red blood cells) typically by day 3-4 of treatment , particularly with injectable forms, though the full resolution of symptoms may take several weeks to months