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doi:10.1177/0960327113506723 Joshi EM, Heasley BH, Macdonald TL (2009) 2-ABT-S-oxide detoxification by glutathione S-transferases A1-1, M1-1 and P1-1: implications for toxicity associated with zileuton

Since the current study collected serum on day 1, this may indicate that the increase in TCA occurs early and then cysteine is utilized for glutathione synthesis rather than for taurine biosynthesis, which results in decreased concentrations of the taurine conjugates

At 25 degrees Celsius (room temperature), hydrolysis accelerates significantly