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DNA methylation as a therapeutic target for cancer treatment In recent years, the development of epidrugs (e.g., DNMT inhibitors, histone deacetylase [HDAC] inhibitors, histone methyltransferase [HMT] inhibitors) has garnered extensive attention as a promising therapeutic option for the treatment of both hematological malignancies and solid tumors [290,291,292]

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PTGS2, Prostaglandin-endoperoxide synthase 2