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Several cellular, biochemical or electrophysiological mechanisms are responsible for CNP, of which neuronal and glial hyperexcitability, microglial activation, and alterations in somatosensory cortical reorganization majorly contribute

Sakaki et al

The first step is the combination of amino acids glutamate and cysteine by -glutamyl cysteine synthetase, also known as glutamate-cysteine ligase (GCL), to form gamma-glutamate-cysteine (-Glu-Cys) (Bottino et al., 2021, Lu, 2013, Wu et al., 2004)

It is strictly designated for laboratory research only and is not approved for human or animal administration

A 51-year-old woman with splenomegaly and anemia
