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Interestingly, a recent report identified that the E3 subunit of PDHC can be nitrosylated (the specific cysteine site was not identified), which inhibits its activity in activated macrophages 9

KZ: Writing original draft

Kovalchuk AL, Qi CF, Torrey TA, Taddesse-Heath L, Feigenbaum L, Park SS, et al
Both pathways act through a caspase activation cascade
Raouf, J
