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Mice were between 12 and 14 weeks of age at the time of experimentation

and suppressed the expression of NADPH oxidase 1(NOX1), NADPH oxidase 4(NOX4), mitogen-activated protein kinase, NF-B, and pro-fibronectin expression

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65 Other studies of cNF have observed signs of microsatellite instability with no accompanying somatic mismatch repair gene mutations in cNF tumour samples, and have observed only a few cNF tumours with somatic mutations in TP53 and RB1