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The first 30 principal components were used for unsupervised cell clustering with a resolution = 0.3, yielding a total of 22 cell clusters using the FindNeighbours and FindClusters functions

While showing promise in inflammatory and cancer disease models, these approaches face clinical translation challenges including DAMP molecular heterogeneity, inefficient drug delivery systems, and the complexity of multi-target synergistic mechanisms

Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis

In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization

In vivo iron-sulfur cluster formation