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Neuroimaging studies provide additional support for central neuroinflammation in ME/CFS
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Additionally, JAB1 interacted with the DID domain of CUL4B and the BPA domain of DDB1, while DDB1 and CUL4B interacted with the MPN enzymatic domain of JAB1

Appleton & Lange, 331-343, 1995

These findings suggest that PRDX1 acts as a potential protective factor in RA pathogenesis
