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Cumulative DNA damage by repeated low-dose cisplatin injection promotes the transition of acute to chronic kidney injury in mice

In vitro , the activated HGF binding to the c-Met drives the phosphorylation of c-Met tyrosine residues, then Wnt-independent nuclear translocation of -catenin is induced by HGF (Monga et al., 2002)
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[DOI] [PubMed] [Google Scholar] [84].Barber VS, Griffiths HR

Those with conditions like pernicious anemia may need lifelong B12 therapy