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Lehninger Principles of Biochemistry (Macmillan, 2008)

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Bachhawat A.K., Yadav S

They suppress immunity with their abundant sugary, starchy, and salty calories

This latter finding is of particular interest, as rather than simply modifying the PDHc, glutarate formed a fatty acid conjugate that binds to the lipoylated catalytic arm of PDHc

This leads to non-receptive endometrium with increased epithelial and decreased stromal proliferation, and exogenous LIF fails to rescue implantation, indicating additional ARID1A-dependent defects ( Transcription factor BCL6 is upregulated in endometriotic lesions and correlates with disease severity and poor IVF outcomes
