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doi: 10.1016/0092-8674(93)90529-y 17 BushatiNCohenSM
Similarly, SPR994, a prodrug known as Terbipenem, is a carbapenem hydrobromide salt esterified with a pivoxil promoiety

Sakaguchi S, Yamaguchi T, Nomura T, Ono M

This preventive effect was abrogated in PPAR-alpha knockout mice, or when animals received a PPAR-alpha antagonist, suggesting that the effects of fenofibrate against DR are PPAR-alpha mediated [30]

These pathways induce downregulation of tight junction protein expression, their mislocalization, and actin cytoskeleton reorganizationcollectively compromising barrier integrity [19]