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Description
Mechanistically, DMF regulates the expression of factors involved in the de novo cysteine synthesis (CBS), cystine uptake (SLC7A11), and GSH generation (GCLC, GCLM) through NRF2-dependent and independent pathways
Recall, irbesartan (Sanofi's Avapro) produced peak sales over $1.2 billion
Common side effects may include local irritation or discomfort, while systemic side effects could include allergic reactions
Boumenjel, A., Pantera, A., Papadopoulos, A
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