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Description
It drives inflammation, insulin resistance, and cardiovascular disease risk far more than subcutaneous fat (the kind you can pinch)
This is why many people find that a monthly injection frequency is the sweet spot for maintaining consistent energy levels

Xu X, Yuan X, Li N, Dewey WL, Li PL, Zhang F

In animal-model work, NNMT inhibition with 5-Amino-1MQ has been associated with changes in adipose-tissue mass, in NAD+ pool sizes (because NNMT consumes nicotinamide that would otherwise feed the NAD+ salvage pathway), and in methyl-donor dynamics (because NNMT consumes S-adenosylmethionine)

The Modern Guide to an Effective Appetite Suppressant: How GLP-1s Changed the Game Struggling to silence food noise in Doral, FL