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Some tumor suppressor genes, including p53 and interferon, have been demonstrated to inhibit SLC7A11 expression, thereby inhibiting cystine uptake and sensitizing cells to ferroptosis (112115)
When the medium condition was changed to PDB medium, the strain Aspergillus terreus produced an unreported compound, 8-hydroxy-2-[1-hydroxyethyl]-5,7-dimethoxynaphtho[2,3-b]thiophene-4,9-dione ( 180 ) (Deng et al
In the following, we summarize the pathophysiological mechanisms of PD in relation to glucose metabolism impairment (Fig
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