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La evidencia en humanos es limitada y en gran parte cosmtica

Moreover, curcumin has been known to prompt a tolerogenic state in DCs by hindering the expression of maturation markers, cytokines, and chemokines, thereby impeding the response of DCs to immune-stimulating agents

Johns wort is safe when used topically

102 Exposure to mercury can induce oxidative stress and trigger inflammatory responses in immune cells by producing ROS
