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[76] pre-treated ADMSCs with SAG, as a specific signal agonist of the Shh signalling pathway, and found that the combination of SAG and TGF-3 significantly increased the gene and protein expression of NP-specific markers at the molecular level as well as the macromolecular level, and significantly changed the IVD height, water content, ECM content, and structure (Table 5)

MDA levels, an indicator of lipid peroxidation and oxidative stress, were measured using a commercial Thiobarbituric Acid Reactive Substances assay kit (abcam, E-BC-K298-M, Cambridge, UK) and absorbance was read at 532 nm

Care 32 , 10231025 (2009)

10.1158/1078-0432.CCR-11-2000 69 ChuK

mRNA has a short half-life, which can be regulated by molecular design