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"The effects of L-carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials." Obesity (Silver Spring)

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As mitochondria fail to maintain cellular energy, neuronal survival is compromised, and apoptotic pathways are activated (Davidson et al., 2001) (Figure 1)

Subjects were instructed to only ascend or descend in response to an audible metronome beep at a cadence of one second downward followed by one second upward