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Description
Duobamycin hydroxybenzamide-azaindole (DUBA) exhibits potent efficacy as a DNA-damaging agent through the tight binding of its cyclopropane ring to the DNA cleavage groove and the alkylation of adenine at the N 3 site
Systemic lupus erythematosus (SLE) and rheumatoid arthritis have been noted in case reports
A synergistic, multitargeted approach may eventually transform this devastating disease into a controllable chronic one
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