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Therefore, partial correlations were performed with age, sex and all comorbidities as covariates, which revealed positive associations between serum concentrations of tumor necrosis factor (TNF), interleukin-6 (IL-6), IL-1 and IP-10 with COVID severity and an inverse association with plasma protein S (Extended Data Fig

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doi: 10.1016/j.bbi.2015.09.013 504 TanakaSKuratsuneHHidakaYHakariyaYTatsumiK-ITakanoTet al

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