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During development of the myeloid lineage, GPX1 and GPX4 expression turns out to drastically increase, notably in human common myeloid progenitors (CMP), granulocytes-monocytes progenitors (GMP), megakaryocyte-erythroid progenitors (MEP) and in monocytes, while it remains very low in polymorphonuclear cells (PMN) (Fig

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