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Jensen JS, et al

Interestingly, pro-inflammatory macrophages rely more on aerobic glycolysis, while anti-inflammatory macrophages are known to be more dependent on OXPHOS [9]

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Once fatty acids are inside mitochondria, they undergo the process of -oxidation through a series of acyl-CoA dehydrogenase enzymes that mediate the shortening of long-chain fats used to produce ATP