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Naringenin can at least partially induce BC cell inhibition of autophagy and cell proliferation by modulating the FKBP4/NR3C1/NRF2 signaling pathway, while also enhancing DC differentiation and maturation (270)

These cells are also specialized to recognize bacterial-derived molecules, known as prokaryotic-associated molecular patterns, with the help of the Toll-like receptors on the cell surface and the nucleotide-binding oligomerization domain-like receptors in the cytoplasm, which activate defense mechanisms by the secretion of anti-microbial peptides 2

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Thus, homocysteine might be less important in the long-term progression and development of coronary artery disease (Cleophas et al, 2000