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In the case of pronounced absorption disorders, for example as a result of gastritis or after removal of the small intestine, in Crohn's disease, diverticulosis and the so-called blind-loop syndrome, there is a gradual decrease in the vitamin B12 store in the liver, which can turn into a manifest vitamin B12 deficiency

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A list of common conditions besides pernicious anemia associated with a B12 deficiency includes the following: Crohns disease Celiac disease Atrophic gastritis, otherwise known as a thinning of the stomach lining Bacteria or parasites in the intestines Immune system disorders, including Graves disease and lupus Inflammatory bowel disease (IBD) Medications Medications can also interfere with B12 absorption, such as some heartburn medicines and proton pump inhibitors prescribed to diabetics

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