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Bond, J., T.S

The mechanism is well-established

The defection of mitophagy will lead to the accumulation of dysfunctional mitochondria, resulting in the leakage of Cytc into the cytoplasm to induce the activation of the caspase signaling pathway, and contribute to cell death (Sinha et al., 2013
Glutathione, The Well-Kept Secret So wait, what exactly is glutathione

As reported in this review, since the liver diseases previously described have oxidative stress in common for their pathogenesis, it follows that the worsening of oxidative damage contributes to HCC development
