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Many patients with type 2 diabetes take metformin long-term, and studies have shown it can interfere with B12 absorption in the terminal ileum
doi: 10.1016/j.expneurol.2008.04.039
This unique property means systemic abdominal injections can still support localized injuries, just with somewhat reduced local concentration
Documented research protocols reference a figure of approximately 50 mg per administration
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