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As early as the late 1980s, Newsholme and colleagues proposed that the central neurotransmitter 5-HT may serve as a key mediator of central fatigue (Newsholme and Blomstrand, 1995)

High-risk PK or PD interactions between antipsychotic agents (namely haloperidol, pimozide, sertindole, and ziprasidone) and antiretrovirals (darunavir/cobicistat or lopinavir/ritonavir) have been detected, mainly associated with an increase in antipsychotic exposure leading to life-threatening events (e.g

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Obstet 32 (17), 27832789