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In contrast, under oxidative stress NRF2 dissociates from KEAP1 and translocates to the nucleus, where it activates the downstream expression of antioxidative response element (ARE)-containing target genes, many of which have been shown to play a role in defending against ferroptosis [65, 66]

Middle-aged (adult day 6) worms were transferred to empty RNAi plates without any bacteria for 15 min to clear the gut of residual bacteria

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Cheung W, Keski-Rahkonen P, Assi N, Ferrari P, Freisling H, Rinaldi S, Slimani N, Zamora-Ros R, Rundle M, Frost G, et al

After 2 years of age, the levels of the lipids and lipoproteins become quite constant up to adolescence