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Collectively, these results demonstrate that Sororins CTR directly and specifically binds the RAD21-SMC3 interface in a cell-cycle-regulated manner on chromatin, consistent with a model in which Sororin stabilizes cohesion by locking the closed DNA exit gate of cohesin

doi: 10.1002/9781119450467.ch1 23 BetzerO.ShiloM.OpochinskyR.BarnoyE.MotieiM.OkunE.et al
A salt-inducible chloroplastic monodehydroascorbate reductase from halophyte Avicennia marina confers salt stress tolerance on transgenic plants

Treatment efficacy increases, particularly in PD-L1-positive tumors, offering a new hope for TNBC patients (233)

A lot of that confusion clears up when you understand what's happening at the cellular level