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Because cobalamin in normally absorbed from food through the gastrointestinal tract, chronic diseases that adversely affect the ability of the intestines to absorb nutrients (inflammatory bowel disease is an excellent example) can lead to cobalamin deficiency

In addition, 20 age and sexmatched controls were also involved

Stable for 5 days at 2-80C or 10 days at -200C

It is an easy approach consisting in one, or up to four injections of 5-10 ml of the gas mixture per site performed very slowly