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WHAT TO MEASURE For selective screening, a lipoprotein profile after an overnight fast is measured for youth who have a positive family history of premature CVD or dyslipidemia, obesity, multiple CVD risk factors, and for those suspected of having secondary dyslipidemia

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Although mitotic rate is variable, it is low in most cases 9

PLoS ONE 7 , e44315 (2012)

Peripheral Neuropathy: Grade 3 peripheral neuropathy occurred in 8% of patients with mBC (Grade 4=0.4%) and 22% developed a new or worsening neuropathy that had not recovered within a median follow-up duration of 269 days (range 25-662 days)