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(Peck 2021) Metabolism : Phenytoin is metabolized in the liver via CYP 2C9 (~90%) and, to a lesser extent, 2C19 (~10%)
The conversion is not a simple mg-to-mg translation because of the different receptor profiles and potencies
Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells
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K.CulmseeC.et al (2008)
