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Description
In general, the effective amount of an active agent or drug delivery device refers to the amount necessary to elicit the desired biological response

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Prior to being diagnosed with melasma in my early 30s, I referred to these patches as freckles. Eventually, these freckles did not fade in the same way they used to once the winter months hit

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Kornblau SM, Thall P, Walterscheid M, Estrov Z, Keating M, Patel S, Kantarjian H, Estey E, Andreeff M