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The preservation of normal glucose-insulin dynamics with AOD-9604 is important for appetite neutrality, as blood sugar fluctuations and insulin spikes are major drivers of hunger and cravings

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However, healthy individuals with intact B12 metabolism convert cyanocobalamin efficiently

Despite correcting his severe B12 and iron deficiency with supplementation, this child remained delayed 7 months after treatment and upon MRI, still showed signs of inadequate myelination, suggesting that he may never achieve full neurological function

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