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The Association between Plasma Levels of Trimethylamine N-Oxide and the Risk of Coronary Heart Disease in Chinese Patients with or without Type 2 Diabetes Mellitus

Impaired bioenergetics of mitochondria in the colonic epithelium by high fat diet resulted in the increase of luminal bioavailability of oxygen and nitrate, thereby intensifying respiration-dependent choline catabolism of E

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Although data were limited for most conditions in terms of the quantity and quality of the studies I reviewed, the number of studies was insufficient, or the results were not sufficiently homogeneous, overall the effect trends were generally positive for many conditions