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Intranasal administration of edaravone nanoparticles improves its stability and brain bioavailability

These modified ARC reactors operate with a transition-metal catalyst that require a flowing O2gas (such as high purity Zero Air or He/1%O2blendat ~0.3 ml/min mixed into the He carrier gas) to enable complete conversion to CO2at lower temperature (620C) with acceptable reactor life, reduced complexity, and improved robustness

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