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A single molecule of BL can neutralize the neurotoxic effect induced by hydrogen peroxide (H 2 O 2 ) at concentrations 1,5003,000 times higher, thereby mitigating oxidative stress ( + T cell activity and promotes regulatory T (Treg) cell proliferation, contributing to the suppression of inflammatory responses ( PD is a neurodegenerative disorder characterized by core motor symptomsincluding resting tremor, dystonia, and gait disturbancesfrequently accompanied by non-motor manifestations such as dementia, sleep disorders, and autonomic dysfunction ( 2 Protective effects of BL in PD 2.1 What does bilirubin mean for Parkinson's disease

DNA methylation is associated with gene silencing, while hypomethylation is involved with the stimulation of the transcription process (Futscher et al., 2002)

They also uncovered a homeostatic mechanism that Ca2+ depletion can trigger influx of cytosol GSH into ER

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