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In 2017, Williams et al

Researches show that aging, chronic degenerative diseases like Parkinsons, Alzheimers disease are strongly associated with a reduced level of glutathione in brain cells

Mitchell, KG, Parra ER, Nelson DB, Corsini E, Zhang J, Vaporciyan AA, Hofstetter WL, Mehran RJ, Swisher SG, Rice DC , Sepesi B, Walsh GL, Behrens MC, Kalhor N, Weissferdt A, Moran C, Skoulidis F, Wistuba II, Fujimoto J, Roth, JA, Antonoff MB

Most of the evidence pointing to a link between epigenetic mutations induced by chronic- and early-life stress-dysregulated negative feedback mechanisms comes from experimental studies

doi: 10.1016/j.plaphy.2016.04.049
