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10.1172/jci.insight.157621 60 GhafouriB.MatikhanD.ChristidisN.ErnbergM.KosekE.MannerkorpiK.et al

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Any noticeable change is reversed soon after stopping glutathione

Vitamin K compounds (phylloquinone, menaquinone-4/MK4, menadione) exhibit broad-spectrum ferroptosis suppression via a non-canonical FSP1-mediated pathway, identifying them as critical substrates for an endogenous anti-ferroptotic system independent of GSH/GPX4 ( 7.3 Free radical scavengers 7.3.1 Preclinical stage Ferrostatin-1 (Fer-1), a canonical radical-trapping antioxidant (RTA), is a cornerstone of ferroptosis research with robust preclinical efficacy (236)