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In summary, there is substantial evidence regarding the critical role of IGF-1/IGF-1R signaling in the progression of PCa, with studies reporting correlations of IGF-1/IGF-1R with tumor cell proliferation, Gleason score, metastatic disease progression, and clinical outcomes

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It highlights the importance of publishing negative data.'' Further, biotechnology company Phosphagenics which used the drug in an anti-cellulite cream Body Shaper, sold in major stores, said this week it had dumped the ingredient last November after 17 months because it was so useless yet incredibly expensive