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Furthermore, we found that the conjugates retain several desirable properties of platinum agents and anthracyclines

One GxE interaction hit illustrates that the fitness defect in the mitochondrial folate carrier (SLC25A32) KO cells is genetically buffered in galactose due to a lack of substrate in de novo purine biosynthesis

Crystal Structures of Cystathionine -Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time

Loss of PDIA1 increases sulfenylation of Drp1 at Cys644 and enhances Drp1 activity, promoting mitochondrial fragmentation and mtROS production, which ultimately leads to endothelial cell dysfunction (Kim YM

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