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Allosteric modulators Allosteric modulators typically attach to regions distinct from the orthosteric site of receptors, inducing conformational changes to regulate the affinity and/or efficacy of orthosteric ligands, or to directly modulate receptor activity with positive, negative, or neutral effects

Introduction Oxidative stress is able to modulate cell growth [1], [2] and it was traditionally defined as the prevalence of the reactive oxygen species (ROS) over antioxidants [3]

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