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Description
L-ornithine L-aspartate (LOLA) functions at that site as a substrate of the urea cycle and thus intervenes in the lowering of ammonia levels through an increase in the flow of glutamine synthetase (GS) and the urea cycle enzymes
doi: 10.1002/jnr.21722
Activation of this pathway destroyed the expression of tight junction proteins such as zonula occludens-2 (ZO-2), occludin, and vascular endothelial cadherin (VE-cadherin) in endothelial cells, which increased endothelial cell permeability
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Adult Dosage: Adults usually require lower weight-based doses, often totaling 1 to 6 grams per day [4] [2]
