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When the active, reduced form of glutathione (GSH) encounters a reactive oxygen species (ROS)such as a superoxide anion or a hydroxyl radicalit donates a reducing equivalent (an electron or hydrogen atom) to neutralize the threat

Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-B-NLRP3-GSDMD and AMPK-PGC-1 axes

( Nature ) 2004 Cardiac survival T4 activated Akt survival pathway in cardiomyocytes after ischemic injury Smart et al

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To evaluate whether these changes will affect the metabolic profiles induced by hemin, we measured SAM and SAH levels, where SAM accumulation by hemin was reduced by DMF treatment (Fig