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Some peptides are approved medicines for specific medical conditions in certain countries, while others are investigational compounds that are still being studied
These results align with earlier animal studies indicating that elamipretide could counteract the harmful effects of A in the brain of individuals with Alzheimer's disease by fortifying the integrity of mitochondrial membranes and reviving respiratory activity (196) (Table 4)

Furthermore, this work was supported by a research grant from the Danish Diabetes Academy, which is funded by the Novo Nordisk Foundation (grant no

Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

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