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This pain may occur due to SI joint degeneration being more likely in patients with a fusion rather than those without any fused vertebrates

10.1155/2023/5514248 21 El-MaksoudA

The extent to which microbial metabolism significantly affects methionine metabolism in vertebrates is unclear, but there is some evidence that it may be a significant source in invertebrates (Matthews et al., 2020)

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Study sizes are frequently small, endpoints vary, and results are inconsistent across routes of administration