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This results in the recruitment of immune cells and the release of pro-inflammatory cytokines, which in turn influence keratinocyte and fibroblast activity 43 , 47

The pharmacokinetics of the sEVs in blood circulation has been generally investigated via intravenous administration (Gudbergsson et al

Methods for in vitro evaluating antimicrobial activity: A review

Enhanced gene expression in the brain following intravenous administration of lactoferrin-bearing polypropylenimine dendriplex
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