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This has even been achieved in lower eukaryotes such as Saccharomyces cerevisiae , where a significant resistance to chlorambucil and doxorubicin (eight- and 16-fold, respectively) was reported in cells transfected with mammalian GST isozymes (Black et al ., 1990)
Most people with hypothyroidism due to Hashimotos thyroiditis will need lifelong treatment with thyroid hormone replacement (levothyroxine)
