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Doshi et al

10.1016/s0301-0082(02)00126-0 152 RowlandL

Rhinovirus-Induced Exacerbations of Asthma and COPD

In contrast, when we modified R1 with neutral groups containing phenyl or ether moieties to generate 31 or 32 , they exhibited the lowest EC 50 /IC 50 ratios of all DEL7 analogs (0.3/0.5 = 0.6 and 0.4/0.3 = 1.3)
